Expert Videos

Module 1: Understanding Pediatric AML

What is acute myeloid leukemia (AML) in children and adolescents?
Dr. Edward Anders Kolb, cancer and blood disorder expert at Nemours Children's Hospital in Wilmington, Delaware, describes what acute myeloid leukemia (AML) is, where it starts, how it tends to appear when first diagnosed, and at what age AML is most common in children and adults. Dr. Kolb also talks about how the cause of childhood AML is different from the cause in adults, and how treatment may be different.
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What causes AML in children and adolescents?
Edward Anders Kolb, MD, director of the Nemours Center for Cancer and Blood Disorders, explains what causes acute myeloid leukemia (AML) in children and teens and how it affects the body's cells. He discusses the role of genetic mutation and how AML treatment is directed at abnormal cells.
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How common is AML in children and adolescents?
Dr. Edward Anders Kolb, an expert on childhood and adolescent cancers and blood disorders, describes how common acute myeloid leukemia (AML) is in children and adolescents, how the type of AML someone has can make a difference in the outcome of treatment, and how often AML tends to be fatal.
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What are the signs and symptoms of AML in children and adolescents?
In this video, Dr. Edward Anders Kolb, an expert on acute myeloid leukemia (AML), describes typical symptoms of AML in children and adolescents, as well as what causes these symptoms. Dr. Kolb talks about the symptoms and signs you may see, including a rash that can appear in some children with AML.
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What are the risk factors for AML in children and adolescents?
Edward Anders Kolb, MD, director of the Nemours Center for Cancer and Blood Disorders, explains that there are a few specific risk factors for AML in children and adolescents. He describes risks related to Down syndrome and other genetic conditions, as well as the role of previous chemotherapy and radiation, the environment, and the mother's pregnancy. Dr. Kolb explains the main cause behind most cases of childhood and teen AML.
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Can AML be prevented in children and adolescents?
Dr. Edward Anders Kolb of the Department of Pediatrics at Nemours Children's Hospital in Wilmington, Delaware, is an expert in child and adolescent blood disorders, including acute myeloid leukemia (AML). In this video, Dr. Kolb addresses whether AML in children and teens can be prevented and the most common cause of this disease.
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What is the outlook (prognosis) for children and adolescents who have AML?
Expert Edward Anders Kolb, MD, of the Nemours Center for Cancer and Blood Disorders in Wilmington, Delaware, describes how many children and teens with AML are usually cured of their disease, including how many who are cured need to have a bone marrow (stem cell) transplant. He discusses the potential for new treatments to help children with acute myeloid leukemia (AML) as well as the importance of working to avoid future side effects of treatment.
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What are the complications of AML in children and adolescents?
Dr. Edward Anders Kolb, expert in children's cancer and blood disorders from Nemours Children's Hospital, describes the effects of treatment for acute myeloid leukemia (AML) on children and teens. He addresses potential effects of different chemotherapy drugs used for AML, how the healthcare team watches for possible complications, which side effects are temporary and which may be lasting, and how doctors and parents or caregivers can work together to reduce side effects of AML and treatment.
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What are the subtypes of AML in children and adolescents?
Edward Anders Kolb, MD, Director of the Nemours Center for Cancer and Blood Disorders, describes the different types of acute myeloid leukemia (AML) doctors may see in children and teens with this cancer. He discusses acute promyelocytic leukemia (APL), Down syndrome, and other leukemia types related to genetic mutations and the outlooks for each type. Dr. Kolb also talks about the main treatment option for AML that comes back after treatment, called relapsed AML.
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What questions should I ask my doctor about AML in children and adolescents?
Listen to expert Dr. Edward Anders Kolb of Nemours Children's Hospital in Wilmington, Delaware, talk about what questions parents and caregivers may want to ask if their child has acute myeloid leukemia (AML), including the likely outcome of treatment, genetic mutations present, about genetic mutations, how well treatment is working, and what to do about side effects. Dr. Kolb explains why it is important to make plans for care and testing after AML treatment and when a child can be considered cancer-free.
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